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Updated: Nov 9, 2025

Generation of Escape Variants of Neutralizing Influenza Virus Monoclonal Antibodies
07:55

Generation of Escape Variants of Neutralizing Influenza Virus Monoclonal Antibodies

Published on: August 29, 2017

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SARS-CoV-2の免疫低下宿主における進化は,共有された中和脱出メカニズムを明らかにする

Sarah A Clark1, Lars E Clark1, Junhua Pan1

  • 1Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.

Cell
|April 8, 2021
PubMed
まとめ

SARS-CoV-2のスパイクタンパク質RBDの変異は,ウイルスが一般的な抗体反応を回避するのに役立ちます. これらの発見は,スパイクタンパク質を標的としたワクチンと治療法の長期的な有効性を理解するために重要である.

キーワード:
コロナウイルスSARS-CoV-2についてアフィニティの成熟抗体中和免疫不全の宿主中和脱出懸念される変種

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