大人のビタミンD欠乏症のスクリーニング:米国の予防サービスタスクフォースの勧告声明

, Alex H Krist^1,2, Karina W Davidson³

¹Fairfax Family Practice Residency, Fairfax, Virginia.

JAMA

|April 13, 2021

まとめ

症状のない成人のビタミンD欠乏症のスクリーニングは,十分な証拠がないため推奨されません. 米国予防サービスタスクフォースは明確な利益や害は見つかりませんでしたこの集団のバランスは不確実です

科学分野:

内分泌学と代謝
予防医学
臨床栄養について

背景:

ビタミンDは,カルシウムホメオスタシス,骨代謝,および様々な細胞機能に不可欠です.
最適なビタミンDレベルと欠乏症の基準は普遍的な合意がない.
個々のビタミンDの必要性は大きく異なります.

研究の目的:

ビタミンD欠乏症のスクリーニングの利害を体系的に検討する.
予防サービスタスクフォース (USPSTF) の2014年の勧告を更新する.
無症状の成人のスクリーニングと早期治療の有効性を評価する.

主な方法:

既存の証拠の体系的な検討を委託した.
欠乏症の症状のないコミュニティで暮らす妊娠していない成人に焦点を当てています
利益と害のスクリーニングと早期治療の結果に関する研究が含まれています.

主要な成果:

ビタミンD欠乏症のスクリーニングの利点に関する全体的な証拠は不足していることが判明しました.
無症状の成人のスクリーニングの利益と害のバランスを決定することができなかった.
USPSTFは不十分な証拠を示す"I声明"を発行した.

結論:

症状のない成人のビタミンD欠乏症のスクリーニングの利益と害を評価するには,現在の証拠は不十分です.
USPSTFは,この集団におけるスクリーニングの純利益を決定することはできません.
スクリーニングと早期治療の役割を明確にするためにさらなる研究が必要です.

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