関連する実験動画

Updated: Nov 9, 2025

An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness
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An Ecdysone Receptor-based Singular Gene Switch for Deliberate Expression of Transgene with Robustness, Reversibility, and Negligible Leakiness

Published on: May 7, 2018

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転写因子の発現と活性を分離することで,ディマースイッチの遺伝子調節が可能になる

C Ricci-Tam1, I Ben-Zion1, J Wang2

  • 1Department of Systems Biology, Harvard Medical School, Boston, MA, USA.

Science (New York, N.Y.)
|April 16, 2021
PubMed
まとめ

酵母における遺伝子調節は"ディマー・スイッチ"メカニズムを使用しています これには単一の転写因子の階層的な制御が含まれ,環境の変化に応じて細胞が精密に遺伝子発現を調整することを可能にします.

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