関連する実験動画

Updated: Nov 8, 2025

Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement
08:06

Genome-wide Determination of Mammalian Replication Timing by DNA Content Measurement

Published on: January 19, 2017

8.6K

複製のタイミングは,ヒト細胞の全体的な表遺伝子状態を維持します

Kyle N Klein1, Peiyao A Zhao1, Xiaowen Lyu2,3

  • 1Department of Biological Science, Florida State University, Tallahassee, FL 32306, USA.

Science (New York, N.Y.)
|April 23, 2021
PubMed
まとめ

RIF1の喪失はDNA複製のタイミングプログラムを排除し,クロマチンの改変とゲノム構造を変化させます. これは 複製のタイミングが グローバルな表遺伝子状態を維持するために 極めて重要であることを示唆しています

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