アスガルドの古生物の多様性とそのユカリオットとの関係
Yang Liu1, Kira S Makarova2, Wen-Cong Huang1
1Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, P. R. China.
Nature
|April 29, 2021
まとめ
この研究は アスガルドの古生物の系統を 新しいゲノムで拡張し 複雑な進化的関係を明らかにした ユカリオットの古代の祖先における水平遺伝子の移転を強調し 生命の初期進化の理解に影響を与えました
科学分野:
- 微生物学と進化生物学
- ゲノミクスと系統遺伝学
- ユカリオットの起源
背景:
- アスガルドの古代生物は ユカリオットに最も近い 古代生物である.
- アルカイア内の真核の祖先の正確な系統遺伝的位置は議論されている (アスガルドとすべてのアルカイアの姉妹の間で).
研究 の 目的:
- アスガルドの古生物のゲノムを比較分析する
- アスガルドの古生物の遺伝的多様性を拡大し ユカリオットの起源を調査する
主な方法:
- 162の完全またはほぼ完全なアスガルド古生物のゲノムを比較分析した.
- 75の新型メタゲノム組み立てゲノムを組み込んだ 系統遺伝学分析
- タンパク質領域の総合分析
主要な成果:
- アスガルドの古生物の遺伝的多様性が大きく拡大し,ウコンガルカイオタを含む6つの新種が提案された.
- 系統遺伝学的な分析は,アスガルド内またはより深い古代の枝として,真核生物の祖先のための2つの可能な配置をサポートしています.
- アスガルドの古生物における拡張した真核シグネチャータンパク質の識別,動的進化を示している.
結論:
- この研究はアスガルドの古生物の多様性と進化について 総合的な見解を提供する.
- 証拠によると,広範囲にわたる水平遺伝子の移転が,真核生物の祖先における古代の"真核体"に寄与した.
- ユカリオットの正確な起源は解明されていないが,アスガルドの古生物と強く結びついている.
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