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Updated: Nov 7, 2025

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics
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アクチン標的型マクロライド誘導体は,がん細胞の運動性と細胞外マトリックスへの侵入を阻害する

Bhavin V Pipaliya1, Daria N Trofimova2, Rebecca L Grange1

  • 1Department of Chemistry, Queen's University, 90 Bader Lane, Kingston ON K7L 3N6, Canada.

Journal of the American Chemical Society
|May 3, 2021
PubMed
まとめ

海洋マクロリド派生体であるMycalolide B (MycB) は,アクチン細胞骨格を標的として,がん細胞の移動と侵入を効果的に阻害する. この発見は 抗転移薬の開発に 新たな戦略を提示しています

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