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Updated: Nov 6, 2025

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
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A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis

Published on: February 16, 2020

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水素結合と分散相互作用によって可能となる同型アミンのエナチオ選択的,触媒的多成分合成

Elisabetta Ronchi1, Shauna M Paradine1, Eric N Jacobsen1

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States.

Journal of the American Chemical Society
|May 5, 2021
PubMed
まとめ

この研究では,チオウレア触媒を用いてアセタールからキラル型ホモアリル型N-Bocアミンを生成するための新しい1段階の方法が紹介されています. このプロセスは,イミニウムイオンをアルリシランで選択的に捕獲することによって,エナティオメリックに濃縮されたアミンを効率的に生成します.

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