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Updated: Nov 6, 2025

Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation
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Resin-Assisted Capture Coupled with Isobaric Tandem Mass Tag Labeling for Multiplexed Quantification of Protein Thiol Oxidation

Published on: June 21, 2021

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NOS ブリッジを備えたライシン-システイン・レドックス・スイッチが酵素機能を調節する

Marie Wensien1,2, Fabian Rabe von Pappenheim1,2, Lisa-Marie Funk1,2

  • 1Department of Molecular Enzymology, Göttingen Center of Molecular Biosciences, Georg August University Göttingen, Göttingen, Germany.

Nature
|May 6, 2021
PubMed
まとめ

研究者らは,新型のシステイン-ライシンクロスリンクを発見し,それをNOSブリッジと名付け,トランスアルドラーゼにおける酸化還元スイッチとして作用した. このスイッチは酵素の活性を調節し 生涯にわたって維持され 新しい治療標的を提示します

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