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Updated: Nov 6, 2025

JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics
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JUMPn: A Streamlined Application for Protein Co-Expression Clustering and Network Analysis in Proteomics

Published on: October 19, 2021

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二重プロテオームスケールのネットワークは,ヒトのインタラクトームの細胞特有の改造を明らかにする

Edward L Huttlin1, Raphael J Bruckner1, Jose Navarrete-Perea1

  • 1Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|May 7, 2021
PubMed
まとめ

この研究はヒトの細胞内の タンパク質の相互作用をマッピングし ネットワークが細胞の機能を 組織する仕組みを明らかにしています 2つの細胞タイプを比較すると 共有されたコア相互作用と 細胞特有のタンパク質組織を定義する ユニークなカスタマイズが見られます

キーワード:
AP-MS についてバイオプレックスバイオ情報学細胞特異性コンピュータ生物学人間のインタラクタームネットワーク生物学タンパク質の相互作用プロテオミクスプロテオタイプ

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