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Updated: Nov 6, 2025

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葉酸ケージ型PROTACによるがん選択的標的分解

Jing Liu1, He Chen2, Yi Liu1

  • 1Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, United States.

Journal of the American Chemical Society
|May 10, 2021
PubMed
まとめ

この研究では,がん治療のための葉酸結合タンパク質分解標的キメラ (PROTACs) が導入されました. これらの新しいPROTACは,がん細胞の標的タンパク質を選択的に分解し,正常な組織における毒性を減少させます.

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