Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Regioselectivity of Electrophilic Additions to Alkenes: Markovnikov's Rule02:17

Regioselectivity of Electrophilic Additions to Alkenes: Markovnikov's Rule

15.2K
If a set of reactants can yield multiple constitutional isomers, but one of the isomers is obtained as the major product, the reaction is said to be regioselective. In such reactions, bond formation or breaking is favored at one reaction site over others.
The hydrohalogenation of an unsymmetrical alkene can yield two haloalkane products, depending on which vinylic carbon takes up the halogen. However, one product usually predominates, where hydrogen adds to the vinylic carbon bearing the...
15.2K
Regioselectivity and Stereochemistry of Hydroboration02:36

Regioselectivity and Stereochemistry of Hydroboration

8.7K
A significant aspect of hydroboration–oxidation is the regio- and stereochemical outcome of the reaction.
Hydroboration proceeds in a concerted fashion with the attack of borane on the π bond, giving a cyclic four-centered transition state. The –BH2 group is bonded to the less substituted carbon and –H to the more substituted carbon. The concerted nature requires the simultaneous addition of –H and –BH2 across the same face of the alkene giving syn stereochemistry.
8.7K
Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry01:29

Diels–Alder Reaction Forming Bridged Bicyclic Products: Stereochemistry

5.0K
Diels–Alder reactions between cyclic dienes locked in an s-cis configuration and dienophiles yield bridged bicyclic products.
5.0K
[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction01:16

[4+2] Cycloaddition of Conjugated Dienes: Diels–Alder Reaction

11.1K
The Diels–Alder reaction is an example of a thermal pericyclic reaction between a conjugated diene and an alkene or alkyne, commonly referred to as a dienophile. The reaction involves a concerted movement of six π electrons, four from the diene and two from the dienophile, forming an unsaturated six-membered ring. As a result, these reactions are classified as [4+2] cycloadditions.
11.1K
Electrophilic 1,2- and 1,4-Addition of HX to 1,3-Butadiene01:17

Electrophilic 1,2- and 1,4-Addition of HX to 1,3-Butadiene

6.7K
The electrophilic addition of hydrogen halides such as HBr to alkenes and nonconjugated dienes gives a single product as per Markovnikov’s rule.
6.7K
Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration02:34

Regioselectivity and Stereochemistry of Acid-Catalyzed Hydration

8.9K
The rate of acid-catalyzed hydration of alkenes depends on the alkene's structure, as the presence of alkyl substituents at the double bond can significantly influence the rate.
8.9K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Ligand-enabled distal desaturative lactonization of aliphatic acids.

Nature·2026
Same author

Fe(porphyrin)-Catalyzed Alkene Epoxidation with NaOCl: A Practical Small- and Large-Scale Alternative to <i>m</i>CPBA.

Journal of the American Chemical Society·2026
Same author

Ligand-Controlled Pd(II)-Catalyzed α,β-Unsaturation and β-Arylation of Long-Chain Acids.

Journal of the American Chemical Society·2026
Same author

Near-Infrared-Light-Driven Photochemistry and Photocatalysis: Mechanisms, Recent Applications, and Opportunities in Organic Synthesis and Biology.

Angewandte Chemie (International ed. in English)·2026
Same author

Ligand Design Enables Introduction of Nonaromatic Arylating Agents in Palladium-Catalyzed C-H Arylation of Arenes.

Journal of the American Chemical Society·2026
Same author

Engineering Isoquinoline-derived Directing Template for Distal C5-H Functionalization of Bicyclic Aza-arenes.

Angewandte Chemie (International ed. in English)·2025
Same journal

Erratum for the Research Article "Detecting supramolecular organic nanoparticles during heat wave".

Science (New York, N.Y.)·2026
Same journal

Local signals, systemic decline.

Science (New York, N.Y.)·2026
Same journal

The mechanics of liver regeneration.

Science (New York, N.Y.)·2026
Same journal

Computing in a memory with physics.

Science (New York, N.Y.)·2026
Same journal

Retraction.

Science (New York, N.Y.)·2026
Same journal

Making time.

Science (New York, N.Y.)·2026
関連記事をすべて見る

関連する実験動画

Updated: Nov 5, 2025

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
07:36

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

8.2K

ディスタルC ((sp2) -H機能化によるアレンの多様化

Uttam Dutta1, Sudip Maiti1, Trisha Bhattacharya1

  • 1Indian Institute of Technology Bombay, Powai, Mumbai 400076, India.

Science (New York, N.Y.)
|May 14, 2021
PubMed
まとめ
この要約は機械生成です。

このレビューは,移行金属触媒による遠端C-H活性化における進歩をカバーしています. サイト選択機能化のための戦略を強調し,メタおよびパラ-C-H結合の活性化における課題を克服します.

さらに関連する動画

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

14.0K
Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
09:35

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

11.8K

関連する実験動画

Last Updated: Nov 5, 2025

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy
07:36

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

8.2K
Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
06:34

Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS

Published on: June 20, 2014

14.0K
Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
09:35

Preparation of a Corannulene-functionalized Hexahelicene by CopperI-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units

Published on: September 18, 2016

11.8K

科学分野:

  • 有機化学
  • カタリシス
  • 合成方法論

背景:

  • 移行金属触媒によるC-H活性化は,効率的な合成経路を提供します.
  • ディスタルC-H活性化 (メタ/パラ) は,ステリックおよび電子的要因のために困難です.
  • サイト選択機能化は複雑な分子合成の鍵です.

研究 の 目的:

  • ディスタルアリルC-H活性化を制御するための最近の戦略をレビューする.
  • メタおよびパラ機能化の課題を克服する方法を強調する.
  • C-H活性化のための触媒とリガンド設計の進歩を紹介する.

主な方法:

  • グループ戦略の指導に関する文献のレビュー
  • 暫定的な仲介者や 跡形のない取締役の分析
  • 触媒における非共性相互作用の検討
  • 選択性に対する触媒とリガンドの効果の評価

主要な成果:

  • ディスタルC-H活性化のための成功方向グループ支援の実証.
  • 新規の短時間・無痕の指揮戦略の探求
  • 地域選択性における非共性相互作用の役割を理解する.
  • ディスタル活性化のための主要な触媒とリガンドの特徴の特定.

結論:

  • ディスタルC-H活性化は,洗練された触媒とテンプレート設計によって達成可能である.
  • メタおよびパラ機能化の固有の課題を克服するために複数の戦略が存在します.
  • このレビューは,サイト選択性C-H機能化の進歩に関する洞察を提供します.