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Updated: Nov 4, 2025

Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication
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Author Spotlight: Characterizing Novel Enzymes from Extremophiles and Common Pathogens to Understand DNA Repair and Replication

Published on: July 5, 2024

969

新しい多核RiPP天然製品に単一およびバイサイクル ω-エステルマクロサイクルをインストールする二重機能ATPグリップリガスの構造的基礎

Gengxiang Zhao1, Dalibor Kosek2, Hong-Bing Liu1

  • 1Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States.

Journal of the American Chemical Society
|May 24, 2021
PubMed
まとめ

研究者は,リボソームで合成され,翻訳後に改変された新しい多核ペプチド (RiPP) を特徴付けました. この研究は,ATP-グラスプリガゼCdnCによるRiPP生物合成における ω-エステル結合形成の構造的基礎を明らかにした.

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