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Updated: Nov 3, 2025

3D Culturing of Organoids from the Intestinal Villi Epithelium Undergoing Dedifferentiation
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トレーシング 腸の幹細胞ニッチの腫瘍遺伝子駆動改造

Min Kyu Yum1,2, Seungmin Han1,2, Juergen Fink2

  • 1Wellcome Trust-Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.

Nature
|June 3, 2021
PubMed
まとめ

新しいRed2Oncoマウスモデルは 癌細胞がマイクロ環境を再構成する方法を示しています 腫瘍遺伝子を発現する腫瘍細胞は,正常な組織に有害なニッチを作り,癌のクローンの成長を促します.

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