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Updated: Nov 3, 2025

Isolation and Flow Cytometric Analysis of Glioma-infiltrating Peripheral Blood Mononuclear Cells
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分泌されるゲルソリンは,DNGR-1依存のクロスプレゼンテーションとがん免疫を抑制する

Evangelos Giampazolias1, Oliver Schulz1, Kok Haw Jonathan Lim2

  • 1Immunobiology Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.

Cell
|June 3, 2021
PubMed
まとめ

分泌されたゲルソリン (sGSN) は,デンドリット細胞の抗原吸収を阻害することによって,抗がん免疫反応を抑制する. sGSNの減少は抗腫瘍免疫と免疫療法の有効性を高め,がん治療の新たな標的を明らかにします.

キーワード:
CLEC9ADNGR-1 についてF-アクチンがんに対する免疫クロスプレゼンテーションデンドリット細胞分泌されたゲルソリン

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