21世紀のHDL:将来のHDL研究のための多機能ロードマップ
Anand Rohatgi1, Marit Westerterp2, Arnold von Eckardstein3
1Department of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas (A. Rohatgi).
Circulation
|June 7, 2021
まとめ
高密度脂質コレステロール (HDL-C) の低レベルは様々な病気に関連していますが,HDL-Cをターゲットにすることは失敗しています. 将来の治療は,よりよい患者の結果のためにHDL機能を最適化することに焦点を当てなければなりません.
科学分野:
- 心血管医学
- 脂質代謝
- 生物化学
背景:
- 低高密度脂質コレステロール (HDL-C) は,生活様式,代謝,心血管疾患のリスク増加に関連した,動脈性脂質不全症のマーカーです.
- 炎症性疾患や悪性腫瘍や 糖尿病とも関係がありますが HDL-Cを上げることは 治療策として成功していません
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