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Updated: Nov 2, 2025

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

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イソメリ化ナイトロンとα-ケトエステルエノラートによる触媒非対称性ダイアステレオ収束 (3 + 2) サイクル添加のダイナミクス

Tetsuya Ezawa1,2, Yoshihiro Sohtome1,2, Daisuke Hashizume3

  • 1Synthetic Organic Chemistry Laboratory, RIKEN Cluster for Pioneering Research, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.

Journal of the American Chemical Society
|June 10, 2021
PubMed
まとめ

この研究では,隣接するステレオセンターを持つ複雑な分子を作るためのNi ((II) 触媒反応を導入します. この方法は,複数の反応種でも高い選択性を達成し,貴重な化学的構成要素を合成するための新しい経路を提供します.

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