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Updated: Nov 2, 2025

Author Spotlight: Exploring Cellular Processes by Modeling Ligands in Cryo-EM Maps
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Gi結合メタボトロピックグルタミン酸受容体mGlu2およびmGlu4の構造

Shuling Lin1,2, Shuo Han3, Xiaoqing Cai1,4

  • 1CAS Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.

Nature
|June 17, 2021
PubMed
まとめ

メタボトロピックグルタミン酸受容体 (mGluRs) は非対称的に信号を発する. 新しい冷凍-EM構造は,このシグナル伝達の鍵となる非対称受容体二分化であり,mGluR機能の分子基盤を提供する.

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