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関連する概念動画

Fluid Movement Between Compartments01:18

Fluid Movement Between Compartments

2.4K
The force applied by fluids against a surface, known as hydrostatic pressure, initiates the transfer of fluid among different compartments. Within our blood vessels, the blood's hydrostatic pressure is a result of the heart's pumping action. At the arteriolar end of capillaries, hydrostatic pressure (capillary blood pressure) exceeds the opposing colloid osmotic pressure created primarily by plasma proteins like albumin. This discrepancy in pressure propels plasma and nutrients from the...
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Capillarity in Fluid01:19

Capillarity in Fluid

518
Capillarity describes the movement of liquid in small spaces without external forces acting on it. The capillarity is driven by surface tension and adhesive interactions between the liquid and surrounding solid surfaces. This effect is often seen in narrow tubes, porous materials, and fine particles.
Surface tension is crucial to capillarity. It results from cohesive forces between liquid molecules at the liquid-air boundary, forming a skin that resists external forces. When the capillary tube...
518
Types of Fluids01:27

Types of Fluids

598
Fluids can be classified into Newtonian and non-Newtonian fluids based on their response to shear stress. Newtonian fluids have a linear relationship between shear stress and the shear strain rate, following Newton's law of viscosity. Their viscosity remains constant regardless of the shear rate, making their behavior predictable and easier to analyze. Common examples include water, air, oil, and gasoline.
In contrast, non-Newtonian fluids do not follow Newton's law of viscosity, and...
598
The Fluid Mosaic Model01:34

The Fluid Mosaic Model

168.2K
The fluid mosaic model was first proposed as a visual representation of research observations. The model comprises the composition and dynamics of membranes and serves as a foundation for future membrane-related studies. The model depicts the structure of the plasma membrane with a variety of components, which include phospholipids, proteins, and carbohydrates. These integral molecules are loosely bound, defining the cell’s border and providing fluidity for optimal function.
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Transcellular Transport of Solutes01:23

Transcellular Transport of Solutes

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Transcellular transport of solutes is the movement of substances like monosaccharides and amino acids through polarized cells. This transport mechanism is primarily seen in epithelial and endothelial cells aided by membrane transport proteins such as channels and transporters. The tight junctions between these cells confine the membrane proteins to the two sides of the cell. The epithelial cells have distinct apical and basolateral domains. In contrast, the endothelial cells show the luminal...
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Characteristics of Fluids01:31

Characteristics of Fluids

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Fluids differ from solids primarily in their molecular structure and stress response. Solids have tightly packed molecules with strong intermolecular forces, maintaining their shape and resisting deformation. In contrast, fluids have molecules spaced farther apart with weaker forces, allowing them to flow and deform easily.
Fluids, which include both liquids and gases, are substances that deform continuously under shearing stress. For example, water and oil are liquids with molecules that can...
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BioMEMS and Cellular Biology: Perspectives and Applications
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BioMEMS and Cellular Biology: Perspectives and Applications

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細胞流体学

Nikola A Dudukovic1, Erika J Fong1, Hawi B Gemeda1

  • 1Lawrence Livermore National Laboratory, Livermore, CA, USA.

Nature
|July 1, 2021
PubMed
まとめ
この要約は機械生成です。

細胞流動学は3Dプリントされたユニット細胞ベースの構造を用いて,多相流動,輸送,反応を正確に制御します. この革新的なプラットフォームは ガス-液体輸送や 選択的な物質堆積などのアプリケーションで プログラムされた流体行動を可能にします

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Cell Squeezing as a Robust, Microfluidic Intracellular Delivery Platform
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科学分野:

  • 多相流と反応工学
  • バイオインスピレーションとバイオミメティック・システム
  • 先進的な材料と製造方法

背景:

  • 自然界のシステムでは 多段階の輸送が最適化されています
  • 既存の微流体装置は,複雑な多相工程に限られている.
  • 流体制御のための生物学的システムの複製は大きな課題です

研究 の 目的:

  • 決定的多相流動制御のための新しいプラットフォームとしてセルラー流動を導入します.
  • 建築された細胞設計を通じて流体輸送のプログラム性を実証する.
  • ガス-液体輸送,蒸発冷却,CO2キャプチャの応用を探求する.

主な方法:

  • 流体制御のための3Dプリント,ユニットセルベースの構造の開発.
  • 細胞の種類,サイズ,密度を設計して 流れの振る舞いをプログラムします
  • ガス-液体輸送,毛細血管駆動の流れ,そして活発なポンプの実験的な実証.
  • 細胞流体装置内のパターン生成のための選択的金属化.

主要な成果:

  • 発汗と吸収を含む,プログラム可能なガス-液体輸送が実証されています.
  • 3Dセルラー流体装置で 流体とガスの特有経路を展示しました
  • 選択的な金属化が プログラムされたパターンで達成された
  • 設計と予測モデリングを通じて流体輸送の決定的制御を検証した.

結論:

  • セルラー流動学は,3Dの多相輸送と反応を 精密でプログラム可能な制御を提供します
  • 設計された細胞材料と予測モデリングは 決定的な流動制御の鍵です
  • このプラットフォームは 多段階のプロセスにおける 空間と時間の制御に革命をもたらす可能性を秘めています