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Updated: Oct 31, 2025

CD Spectroscopy to Study DNA-Protein Interactions
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プロモーターアンチセンスRNAの形は,リガンド誘発の転写活性化を調節する

Fan Yang1, Bogdan Tanasa2, Rudi Micheletti3

  • 1Howard Hughes Medical Institute, Department and School of Medicine, University of California, San Diego, La Jolla, CA, USA. fay009@health.ucsd.edu.

Nature
|July 1, 2021
PubMed
まとめ

長い非コーディングRNA (lncRNAs),特にプロモーター反意味RNA (PAS) は,P-TEFb複合体を制御することによって遺伝子転写を調節する. PASRNAはデメチラゼを誘導し,構造的な相互作用によって遺伝子の活性化につながります.

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