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Updated: Oct 30, 2025

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
07:12

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

Published on: April 16, 2015

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ポリアミンの代謝は,ヘルパーT細胞系統の忠誠性を決定する中心的要因である

Daniel J Puleston1, Francesc Baixauli2, David E Sanin2

  • 1Max Planck Institute of Immunobiology and Epigenetics, 79108 Freiburg, Germany; The Kennedy Institute of Rheumatology, University of Oxford, Oxford OX3 7FY, UK.

Cell
|July 3, 2021
PubMed
まとめ

ポリアミンの代謝は,CD4+ヘルパーT細胞の分化と機能に不可欠です. その欠乏はT細胞のサブセットの特異性を損ない,表遺伝的変化と炎症性疾患につながります.

キーワード:
T細胞eIF5Aハイプシン免責権免疫代謝メタボリズムポリアミン

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Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function11:50

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