関連する実験動画

Updated: Oct 29, 2025

RNAi Screening for Host Factors Involved in Vaccinia Virus Infection using Drosophila Cells
08:20

RNAi Screening for Host Factors Involved in Vaccinia Virus Infection using Drosophila Cells

Published on: August 25, 2010

9.7K

Dicer の同型は,複数の RNA ウイルスから哺乳類の幹細胞を保護する

Enzo Z Poirier1, Michael D Buck2, Probir Chakravarty3

  • 1Immunobiology laboratory, Francis Crick Institute, London NW1 1AT, UK. enzo.poirier@crick.ac.uk caetano@crick.ac.uk.

Science (New York, N.Y.)
|July 10, 2021
PubMed
まとめ

哺乳類の幹細胞は,新たに発見されたDicerタンパク質同型,抗ウイルスDicer (aviD) によってウイルスから保護されています. このタンパク質は RNA 干渉 (RNAi) を制御し,ウイルスの二重鎖 RNA に対して防御し,先天的な免疫力を高めます.

さらに関連する動画

RNAi Interference by dsRNA Injection into Drosophila Embryos08:30

RNAi Interference by dsRNA Injection into Drosophila Embryos

Published on: April 11, 2011

16.4K
Study of Dendritic Cell Development by Short Hairpin RNA-Mediated Gene Knockdown in a Hematopoietic Stem and Progenitor Cell Line In vitro06:12

Study of Dendritic Cell Development by Short Hairpin RNA-Mediated Gene Knockdown in a Hematopoietic Stem and Progenitor Cell Line In vitro

Published on: March 7, 2022

3.6K

関連する概念動画

Experimental RNAi02:15

Experimental RNAi

RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing its transcription or activating the RNA degradation process. The mechanism was discovered by Andrew Fire and Craig Mello in 1998 in plants. Today, it is observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals. This precise cellular mechanism of gene silencing has been developed into a technique that provides an efficient way to identify and determine the...
6.6K
RNA Interference01:23

RNA Interference

RNA interference (RNAi) is a process in which a small non-coding RNA molecule blocks the post-transcriptional expression of a gene by binding to its messenger RNA (mRNA) and preventing the protein from being translated.
This process occurs naturally in cells, often through the activity of genomically-encoded microRNAs. Researchers can take advantage of this mechanism by introducing synthetic RNAs to deactivate specific genes for research or therapeutic purposes. For example, RNAi could be used...
26.8K
siRNA - Small Interfering RNAs02:30

siRNA - Small Interfering RNAs

Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the...
17.4K
Small interfering RNAs (siRNA)02:30

Small interfering RNAs (siRNA)

3.8K
piRNA - Piwi-interacting RNAs02:57

piRNA - Piwi-interacting RNAs

PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...
7.1K
Viruses with RNA Genomes01:29

Viruses with RNA Genomes

RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
275