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Updated: Oct 28, 2025

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強力な抗生物質候補であるイボクサミシンの実用的なグラムスケール合成

Jeremy D Mason1, Daniel W Terwilliger1, Aditya R Pote1

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States.

Journal of the American Chemical Society
|July 15, 2021
PubMed
まとめ

抗生物質候補であるイボクサミシンをグラムスケールで合成した. この新しい経路は,感染モデルでの in vivo 研究に十分な量を提供します.

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Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
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