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Updated: Oct 27, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
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カーボキシル酸の後期 β-C ((sp3) -H デュテレーション

Alexander Uttry1, Sourjya Mal1, Manuel van Gemmeren1

  • 1Organisch-Chemisches Institut Westfälische Wilhelms-Universität Münster, Corrensstraße 36, 48149 Münster, Germany.

Journal of the American Chemical Society
|July 19, 2021
PubMed
まとめ

研究者たちは,カルボキシル酸の後期デュテレーションのための新しい方法を開発しました. この技術は非活性化されたメチレン結合を機能化し,生物活性分子の改変の可能性を拡大します.

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