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Updated: Oct 27, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
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メラノーマにおける抗腫瘍CD8+T細胞のフェノタイプ,特異性およびアビディティ

Giacomo Oliveira1,2, Kari Stromhaug1, Susan Klaeger3

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.

Nature
|July 22, 2021
PubMed
まとめ

腫瘍抗原の特異性は,メラノーマにおけるCD8+T細胞の表型を決定する. 腫瘍反応性T細胞は疲労を示し,非反応性細胞は記憶現象型を維持し,抗癌免疫に影響する.

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