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Updated: Oct 26, 2025

Using Caenorhabditis elegans as a Model System to Study Protein Homeostasis in a Multicellular Organism
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返品できないのは 普遍的な問題です コリ・プロテオーム

Philip To1, Briana Whitehead2, Haley E Tarbox1

  • 1Department of Chemistry, Johns Hopkins University, Baltimore, Maryland 21218, United States.

Journal of the American Chemical Society
|July 26, 2021
PubMed
まとめ

大腸菌の多くのタンパク質は,生理的な時間尺度では本質的に折りたたまれません. この研究では,質量スペクトロメトリーに基づくプロテオミクスを用いて,溶解性プロテオームの3分の1が効率的なタンパク質折り畳みのために外部要因を必要としていることを明らかにしました.

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