関連する実験動画
Updated: Oct 25, 2025
05:55
Modeling the Functional Network for Spatial Navigation in the Human Brain
Published on: October 13, 2023
1.3K
発達中のコネクトームは,脳の成熟の原理を明らかにする
Daniel Witvliet1,2, Ben Mulcahy3, James K Mitchell4,5
1Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada. daniel.witvliet@gmail.com.
Nature
|August 5, 2021
まとめ
ネマトードワーム
科学分野:
- 神経科学
- 発達生物学
- コネクトミックス
背景:
- 動物の神経系は 生まれてから大人になるまで 大きく変化します
- 発達中の神経回路の改造の程度はほとんど不明です.
研究 の 目的:
- カエノラビティス・エレガンス脳コネクトームの 歳に関係する変化を 調べるために
- 発達過程で 神経線路と情報処理がどのように進化するのかを理解する.
主な方法:
- シリアルセクション電子顕微鏡を用いて,複数のCaenorhabditis elegans個体の完全な脳コネクトームを再構築した.
- 比較的なコネクトミクスは,様々な産後発達段階において用いられました.
主要な成果:
- C.elegansの脳構造は一貫しているが,化学的シナプス結合は大幅な改変を遂げている.
- 個々のコネクトームは 独特の配線パターンを示し 接続性の発達の変化は ニューロン全体に一貫しています
- 神経経路,特に感覚と運動回路は 大きく改造され,情報処理が変化し,年齢とともによりモジュール化され,フィードフォワードの脳構造が生まれます.
結論:
- 脳の成熟と 神経回路の改造に 基づく一貫した原理を明らかにします
- この研究は 神経系の構造と機能が 生涯にわたって どのように変化するかを 洞察します
さらに関連する動画
06:18Author Spotlight: Deciphering Neural Circuit Formation from Two-Photon Microscopy and Single Neuron Imaging
Published on: November 21, 2023
1.0K
13:47Ex utero Electroporation and Whole Hemisphere Explants: A Simple Experimental Method for Studies of Early Cortical Development
Published on: April 3, 2013
13.1K
関連する概念動画
01:22Sutures of the Skull
8.6K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
8.6K
01:30Organization of the Brain
1.6K
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
1.6K
01:20Anatomy of the Brain: Major Regions
7.4K
The brain is the most complex organ in the human body. It consists of four main parts: the cerebrum, diencephalon, cerebellum, and brainstem.
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...
The cerebrum is the largest section of the brain and divides into left and right hemispheres, separated by a deep fissure. The cerebral outer layer of grey matter — the cerebral cortex — comprises elevations called gyri and shallow groves called sulci. The inner portion of white matter includes long nerve fibers known as axons, which connect...
7.4K
01:11Cerebrum: Anatomical Overview II
2.9K
Each cerebral hemisphere can be divided into three main regions. The outermost region, the cerebral cortex, is a thin layer (2 to 4 millimeters thick) made up of gray matter, consisting of neuron cell bodies, dendrites, glial cells, and blood vessels. The middle region, or white matter, is primarily composed of myelinated nerve fibers organized into three types of large tracts: association fibers, commissures, and projection fibers. Association fibers connect different areas within the same...
2.9K
01:18Anatomy of the Brain: Ventricles
5.8K
There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen.
5.8K
01:17Cerebellum: Anatomical Regions
2.7K
The cerebellum, also known as the "little brain," is located in the posterior cranial fossa, inferior to the tentorium cerebelli and dorsal to the brainstem. It plays a significant role in motor control, coordination, and proprioception.
Cerebellar Structure
Externally, the cerebellum features a highly convoluted surface with numerous folia (narrow ridges) separated by shallow sulci (grooves). The cerebellum is divided into two hemispheres by a thin median structure known as the vermis. The...
Cerebellar Structure
Externally, the cerebellum features a highly convoluted surface with numerous folia (narrow ridges) separated by shallow sulci (grooves). The cerebellum is divided into two hemispheres by a thin median structure known as the vermis. The...
2.7K