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Updated: Oct 25, 2025

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Prp5がプレ-mRNAブランチサイトを校正する方法に関する構造的洞察

Zhenwei Zhang1, Norbert Rigo2, Olexandr Dybkov2

  • 1Department of Structural Dynamics, MPI for Biophysical Chemistry, Göttingen, Germany.

Nature
|August 5, 2021
PubMed
まとめ

この研究では,スプライソームのヘリケーズであるPrp5が,間接的にブランチサイトを校正することによって,正確なプレ-mRNAスプライシングを保証する方法を明らかにしました. Hsh155タンパク質が再構成されるまで 組み立てをブロックし 信頼性を確保します

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