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Updated: Oct 22, 2025

Oligopeptide Competition Assay for Phosphorylation Site Determination
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非活性なATP結合状態のAMPK複合体の構造

Yan Yan1, Somnath Mukherjee2, Kaleeckal G Harikumar3

  • 1Department of Structural Biology, Van Andel Institute, Grand Rapids, MI 49503, USA.

Science (New York, N.Y.)
|August 26, 2021
PubMed
まとめ

アデノシンモノフォスファート (AMP) 活性化タンパク質キナーゼ (AMPK) の活動は細胞のエネルギーレベルによって調節されます. 新しい研究は,ATP結合がAMPKを無効にする構造的変化を引き起こし,代謝制御の洞察を提供することを明らかにしています.

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