関連する実験動画

Updated: Oct 22, 2025

Evaluation of T Follicular Helper Cells and Germinal Center Response During Influenza A Virus Infection in Mice
07:07

Evaluation of T Follicular Helper Cells and Germinal Center Response During Influenza A Virus Infection in Mice

Published on: June 27, 2020

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末期生殖中心のT毛細血管ヘルパー細胞によるFoxp3の発現

Johanne T Jacobsen1, Wei Hu2,3, Tiago B R Castro4,5

  • 1Laboratory of Lymphocyte Dynamics, The Rockefeller University, New York, NY, USA. jjacobsen@rockefeller.edu victora@rockefeller.edu.

Science (New York, N.Y.)
|August 26, 2021
PubMed
まとめ

ゲルミナルセンター (GC) の収縮は,Foxp3+ T細胞の増加に先行する. Foxp3のT卵泡ヘルパー細胞の上昇は,GCの寿命と抗体の成熟を調節する可能性があります.

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Isolation of CD4+ T-cells and Analysis of Circulating T-follicular Helper cTfh Cell Subsets from Peripheral Blood Using 6-color Flow Cytometry07:39

Isolation of CD4+ T-cells and Analysis of Circulating T-follicular Helper cTfh Cell Subsets from Peripheral Blood Using 6-color Flow Cytometry

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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol08:20

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The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
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The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
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