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Updated: Oct 22, 2025

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
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9つの集団から826,690人の骨関節炎遺伝子の解読

Cindy G Boer1, Konstantinos Hatzikotoulas2, Lorraine Southam2

  • 1Department of Internal Medicine, Erasmus MC, Medical Center, 3015CN Rotterdam, the Netherlands.

Cell
|August 27, 2021
PubMed
まとめ

この研究では,親指と脊椎骨関節炎の新しいリンクを含む,骨関節炎 (OA) の遺伝的リスクの100の変種が特定されました. この発見は,OAのメカニズムと,この広範囲にわたる関節疾患の潜在的薬物標的についての洞察を提供します.

キーワード:
薬物標的エフェクター遺伝子機能的ゲノミクス遺伝子構造ゲノム全体の関連メタ解析骨関節炎

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