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Updated: Oct 21, 2025

Contact-Free Co-Culture Model for the Study of Innate Immune Cell Activation During Respiratory Virus Infection
07:36

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Published on: February 28, 2021

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呼吸道に沿ったインターフェロンの風景は,COVID-19の重症度に影響します

Benedetta Sposito1, Achille Broggi2, Laura Pandolfi3

  • 1Harvard Medical School, Boston Children's Hospital, Division of Immunology, Boston, MA 02115, USA; Department of Biotechnology and Biosciences and Ph.D. Program in Molecular and Translational Medicine (DIMET), University of Milano - Bicocca, Milan 20100, Italy.

Cell
|September 7, 2021
PubMed
まとめ

インターフェロン (IFN) はCOVID-19において異なる役割を果たします. 上部呼吸道におけるIFNタイプ3は重篤な病気から身を守りますが,下部呼吸道におけるIFNは重篤なCOVID-19病理と関連しています.

キーワード:
コロナウイルスSARS-CoV-2についてタイプI IFNタイプIIIのIFN呼吸道デンドリット細胞皮質細胞インターフェロン肺についてパターン認識レセプター

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