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細胞間CRISPRスクリーンは,がん細胞のファゴシトーシスの調節体を明らかにします

Roarke A Kamber1, Yoko Nishiga1,2,3, Bhek Morton1

  • 1Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.

Nature
|September 9, 2021
PubMed
まとめ

研究者らは,脂肪細胞の血関連タンパク質 (APMAP) が,がん細胞がマクロファージのファゴシトーシスを回避する重要な要因であると特定した. APMAPの喪失は,免疫療法による癌細胞の除去を促進し,新しい治療戦略を提供します.

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