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Updated: Oct 20, 2025

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
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薬剤耐性感染症に対する新しい抗生物質の合理的な設計

Thomas F Durand-Reville1, Alita A Miller1, John P O'Donnell1

  • 1Entasis Therapeutics, Waltham, MA, USA.

Nature
|September 16, 2021
PubMed
まとめ

研究者は薬剤耐性グラム陰性細菌と戦うために,新しい抗生物質ETX0462を開発しました. この新しいダイアザビサイクロオクタン化合物は 主要な抵抗メカニズムを克服し 危険な感染症に対する希望を与えてくれます

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