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Updated: Oct 20, 2025

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UTXの凝縮は,その腫瘍抑制作用の根底にある

Bi Shi1, Wei Li1, Yansu Song1

  • 1Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.

Nature
|September 16, 2021
PubMed
まとめ

腫瘍抑制剤UTX (KDM6Aとしても知られる) は,その機能のために,単にデメチラーゼ活動ではなく,相分離に依存する. 腫瘍抑制と細胞分化に 欠かせない凝縮を引き起こします

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