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Updated: Oct 19, 2025

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イーストDNAポリメラーゼ ε の [4Fe4S] クラスタはレドックス活性であり,DNA媒介によるシグナル伝達を受けることができる

Miguel N Pinto1, Josy Ter Beek2, Levi A Ekanger1,3

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, United States.

Journal of the American Chemical Society
|September 24, 2021
PubMed
まとめ

DNAポリメラーゼ ε (Pol ε) は複製のために [4Fe4S]クラスタを使用する. 酸化は酵素を無効化しますが,潜在的にDNA電荷輸送経由での再縮は活性を再生します.

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