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関連する概念動画

Veins of Head and Neck01:19

Veins of Head and Neck

3.4K
The blood drainage from the head and neck is primarily managed by three pairs of veins: the external jugular, internal jugular, and vertebral veins. The external jugular veins drain superficial scalp and face structures, passing over the sternocleidomastoid muscles to empty into the subclavian veins.
On the other hand, the vertebral veins, unlike their arterial counterparts, are not primarily responsible for brain drainage. Instead, they drain the cervical vertebrae, spinal cord, and some small...
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Arteries of the Head and Neck01:26

Arteries of the Head and Neck

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The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
2.0K
Muscles that Move the Head01:19

Muscles that Move the Head

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The muscles that move the head are a dynamic and complex group of structures that work together to facilitate a wide range of head movements, including rotation, flexion, extension, and lateral bending.
The bilateral sternocleidomastoid, or SCM, and the suprahyoid and infrahyoid muscles are significant head flexors. The SCM muscles originate at the sternum and clavicle and attach to the mastoid process of the temporal bone. The SCM contracts bilaterally to bend the head forward, whereas...
3.7K
Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Cancer Therapies02:49

Cancer Therapies

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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
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Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists01:28

Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists

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Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates...
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Updated: Oct 19, 2025

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
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Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

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頭頸部 がん

Mayur D Mody1, James W Rocco2, Sue S Yom3

  • 1Department of Hematology and Medical Oncology, The Winship Cancer Institute, Emory University, Atlanta, GA, USA.

Lancet (London, England)
|September 25, 2021
PubMed
まとめ

頭頸部がんは 状細胞がんが多く 世界的な問題です 治療には,特定の部位と組織に合わせた多学科的なアプローチが必要で,患者の治療結果を改善することに焦点を当てた研究が進行中です.

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Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
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Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma

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Last Updated: Oct 19, 2025

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
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A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
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科学分野:

  • 腫瘍学
  • 耳鼻喉科

背景:

  • 頭頸部がんは世界で7番目に多い悪性腫瘍で 上部消化管に影響します
  • 状細胞癌は,喫煙,アルコール,ウイルス (HPV,EBV) が主要な危険因子である.
  • これらの悪性腫瘍は 複雑な治療課題を提示し 多分野戦略が必要となります

研究 の 目的:

  • 頭頸部がんに関する現在の理解を総合的に説明する.
  • これらの悪性腫瘍の確立された治療原則に焦点を当てること.
  • 患者の治療成果を向上させるための新たな方向性について話し合うこと

主な方法:

  • 頭頸部がんに関する最新の文献と臨床的理解のレビュー
  • 手術,放射線治療,全身療法を含む既知の治療方法の分析
  • 部位特異性および組織特異性による治療変異の探求

主要な成果:

  • 頭頸部がんは多様で,状細胞癌が最も一般的です.
  • ライフスタイルの選択や ウイルス感染などの リスク要因はよく定義されています
  • 局所的に進行した病気には多科目の治療が不可欠です.

結論:

  • 治療戦略は,がんの部位と組織学に基づいて個別化する必要があります.
  • 継続的な研究と新しい治療方法の探求は不可欠です.
  • 頭頸部悪性腫瘍の治療における主な目標は 患者のアウトカムを改善することです