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Updated: Oct 18, 2025

Genome Editing in Mammalian Cell Lines using CRISPR-Cas
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CRISPR-CasにおけるCas4支援型方向間隔器の取得のためのメカニズム

Chunyi Hu1, Cristóbal Almendros2,3, Ki Hyun Nam4

  • 1Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA.

Nature
|September 30, 2021
PubMed
まとめ

プロカリオットは外来DNAから防御するために CRISPR-Casシステムを使用します Cas4/Cas1 酵素複合体は,正しいスペーサー DNA が CRISPR 配列に統合され,防御システムの方向性を維持します.

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