Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Thermal and Photochemical Electrocyclic Reactions: Overview01:26

Thermal and Photochemical Electrocyclic Reactions: Overview

2.5K
Electrocyclic reactions are reversible reactions. They involve an intramolecular cyclization or ring-opening of a conjugated polyene. Shown below are two examples of electrocyclic reactions. In the first reaction, the formation of the cyclic product is favored. In contrast, in the second reaction, ring-opening is favored due to the high ring strain associated with cyclobutene formation.
2.5K
Electrodeposition01:08

Electrodeposition

788
Electrodeposition is a technique used to separate an analyte from interferents by electrochemical processes. Here, the analyte is a metal ion that can be deposited on an electrode immersed in the sample solution. The electrochemical setup consists of an anode and a cathode. When an electric current is applied to the setup, oxidation occurs at the anode. At the cathode, which consists of a large metal surface, metal ions undergo reduction and deposit onto the surface.
Electrodeposition can...
788
Thermal Electrocyclic Reactions: Stereochemistry01:17

Thermal Electrocyclic Reactions: Stereochemistry

2.2K
The stereochemistry of electrocyclic reactions is strongly influenced by the orbital symmetry of the polyene HOMO. Under thermal conditions, the reaction proceeds via the ground-state HOMO.
Selection Rules: Thermal Activation
Conjugated systems containing an even number of π-electron pairs undergo a conrotatory ring closure. For example, thermal electrocyclization of (2E,4E)-2,4-hexadiene, a conjugated diene containing two π-electron pairs, gives trans-3,4-dimethylcyclobutene.
2.2K
Controlled-Potential Coulometry: Electrolytic Methods01:17

Controlled-Potential Coulometry: Electrolytic Methods

343
Controlled-potential coulometry, also known as potentiostatic coulometry, employs a three-electrode system in which the working electrode's potential is precisely regulated using a potentiostat. Platinum working electrodes are utilized for positive potentials, while mercury pool electrodes are favored for extremely negative potentials. The platinum counter electrode is separated from the analyte using a membrane or salt bridge to avoid interference in the analysis.
The chosen potential...
343
Sharpless Epoxidation02:57

Sharpless Epoxidation

4.4K
The conversion of allylic alcohols into epoxides using the chiral catalyst was discovered by K. Barry Sharpless and is known as Sharpless epoxidation. The use of a chiral catalyst enables the formation of one enantiomer of the product in excess. This chiral catalyst is mainly a chiral complex of titanium tetraisopropoxide and tartrate ester (specific stereoisomer). The stereoisomer used in the chiral catalyst dictates the formation of the enantiomer of the product. In other words, the use of...
4.4K
Photochemical Electrocyclic Reactions: Stereochemistry01:26

Photochemical Electrocyclic Reactions: Stereochemistry

2.0K
The absorption of UV–visible light by conjugated systems causes the promotion of an electron from the ground state to the excited state. Consequently, photochemical electrocyclic reactions proceed via the excited-state HOMO rather than the ground-state HOMO. Since the ground- and excited-state HOMOs have different symmetries, the stereochemical outcome of electrocyclic reactions depends on the mode of activation; i.e., thermal or photochemical.
Selection Rules: Photochemical Activation
2.0K

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Risk Factors for Sacral Insufficiency Fracture After Pelvic Irradiation for Cervical Cancer.

In vivo (Athens, Greece)·2026
Same author

Inherent tissue homeostasis of the juvenile metaphysis provides a foundation for osteosarcoma development.

Nature communications·2026
Same author

C-glycoside synthesis via radical cross-coupling of glycohydrazides.

Nature·2026
Same author

Stereoretentive radical-based alkyl-alkyl cross-coupling.

Science (New York, N.Y.)·2026
Same author

Ultrasound-guided biopsy for thoracic lesions: diagnostic performance, safety, and potential role of contrast-enhanced ultrasound.

Journal of medical ultrasonics (2001)·2026
Same author

A Narrative Inquiry of Meaning Making and Leader Identity Development among College Students.

New directions for student leadership·2026

関連する実験動画

Updated: Oct 18, 2025

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction
10:57

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Published on: April 10, 2018

18.5K

急速な交互の極性を用いた化学選択的電気合成

Yu Kawamata1, Kyohei Hayashi1, Ethan Carlson1

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, United States.

Journal of the American Chemical Society
|October 1, 2021
PubMed
まとめ
この要約は機械生成です。

カーボニル化合物の化学選択的還元は,急速な交互の極性 (rAP) 電解を用いて達成される. この新しい電気化学的方法では 精密な制御が可能で 複雑な有機合成において 従来の直流電解と化学反応剤を上回ります

さらに関連する動画

Simultaneous Multi-surface Anodizations and Stair-like Reverse Biases Detachment of Anodic Aluminum Oxides in Sulfuric and Oxalic Acid Electrolyte
10:27

Simultaneous Multi-surface Anodizations and Stair-like Reverse Biases Detachment of Anodic Aluminum Oxides in Sulfuric and Oxalic Acid Electrolyte

Published on: October 5, 2017

7.4K
Reductive Electropolymerization of a Vinyl-containing Poly-pyridyl Complex on Glassy Carbon and Fluorine-doped Tin Oxide Electrodes
09:17

Reductive Electropolymerization of a Vinyl-containing Poly-pyridyl Complex on Glassy Carbon and Fluorine-doped Tin Oxide Electrodes

Published on: January 30, 2015

12.0K

関連する実験動画

Last Updated: Oct 18, 2025

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction
10:57

Synthesis and Performance Characterizations of Transition Metal Single Atom Catalyst for Electrochemical CO2 Reduction

Published on: April 10, 2018

18.5K
Simultaneous Multi-surface Anodizations and Stair-like Reverse Biases Detachment of Anodic Aluminum Oxides in Sulfuric and Oxalic Acid Electrolyte
10:27

Simultaneous Multi-surface Anodizations and Stair-like Reverse Biases Detachment of Anodic Aluminum Oxides in Sulfuric and Oxalic Acid Electrolyte

Published on: October 5, 2017

7.4K
Reductive Electropolymerization of a Vinyl-containing Poly-pyridyl Complex on Glassy Carbon and Fluorine-doped Tin Oxide Electrodes
09:17

Reductive Electropolymerization of a Vinyl-containing Poly-pyridyl Complex on Glassy Carbon and Fluorine-doped Tin Oxide Electrodes

Published on: January 30, 2015

12.0K

科学分野:

  • 有機化学
  • 電気化学
  • 合成方法論

背景:

  • 有機合成における化学選択性は,伝統的に調節可能な反応剤または保護基に依存している.
  • 電気化学的方法はリドックス制御を提供しますが,複数のリドックス活性サイトと闘います.
  • 直流 (DC) 電解は標準であり,交流 (AC) 効果は準備合成では十分に研究されていない.

研究 の 目的:

  • カルボニル化合物の精密な化学選択的還元のための新しい電気化学的アプローチを開発する.
  • 複雑な有機合成における交流電流 (AC) の戦略的利用を実証する.
  • 合成の課題を克服する際の迅速な交互の極性 (rAP) の有用性を示します.

主な方法:

  • 正方形の波形を用いて,高速変極電流 (rAP) を送る.
  • カルボニル化合物の化学選択的還元を研究している.
  • rAP電解と直流電解と化学反応剤を比較する.

主要な成果:

  • 急速交互の極性 (rAP) 電解は,カルボニル化合物の制御された化学選択的還元を可能にします.
  • rAPで観察された反応性は,DC電解または従来の化学反応剤を使用して再現することはできません.
  • キラル補助除去とPROTAC合成における実証された合成有用性.

結論:

  • 急速交差極性 (rAP) 電解は,有機合成における化学選択性を達成するための強力な新しいツールです.
  • この方法は独特の反応性と制御性を提供し,電気合成の範囲を拡大します.
  • rAP電解は,古典的な合成問題と近代的な医薬品化学の応用の両方に重要な利点を提供します.