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Updated: Oct 17, 2025

Bioluminescent Bacterial Imaging In Vivo
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免疫療法のための遺伝子組み換え細菌による腫瘍の代謝調節

Fernando P Canale1, Camilla Basso1,2, Gaia Antonini1

  • 1Institute for Research in Biomedicine, Università della Svizzera italiana, Bellinzona, Switzerland.

Nature
|October 7, 2021
PubMed
まとめ

エンジニアリングされたバクテリアは 腫瘍内のアンモニアをL-アルギニンに変換することで 抗腫瘍T細胞の反応を高めます このアプローチは免疫チェックポイント阻害剤の有効性を高め,癌の免疫療法に新しい戦略を提供します.

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