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Updated: Jul 30, 2026

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method
16:07

Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method

Published on: September 16, 2017

分化誘発因子と腫瘍死滅因子の同一性

K Takeda, S Iwamoto, H Sugimoto

    Nature
    |September 1, 1986
    PubMed
    まとめ

    人間の骨髄性白血病の細胞は,差別化誘発因子 (DIF) に曝露されたときにマクロファージに微分化します. 研究者はDIFを精製し,このプロセスの重要な要因である腫瘍死滅因子 (TNF) である可能性が高いことを発見しました.

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