関連する実験動画

Updated: Oct 17, 2025

Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange
15:13

Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange

Published on: April 27, 2017

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マウス特有のレトロトランスポソンは,開発に不可欠な保存されたCdk2ap1同型を駆動する.

Andrew J Modzelewski1, Wanqing Shao2, Jingqi Chen1

  • 1Division of Cellular and Developmental Biology, MCB Department, University of California, Berkeley, Berkeley, CA 94720, USA.

Cell
|October 13, 2021
PubMed
まとめ

移植可能な要素,特に長い末端のリピートレトロトランポゾンプロモーターは,哺乳類の初期発達の間に遺伝子調節を駆動する. 種特有のトランポゾンプロモーターは,新しい機能を持つ保存されたタンパク質イソフォームを生成し,発達の相違に影響を与えます.

キーワード:
Cdk2 についてCdk2ap1 について細胞増殖植入する哺乳類マウス移植前の胚プロモーターレトロトランスポゾントランポゾン

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Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development09:32

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PIWI-interacting RNAs, or piRNAs, are the most abundant short non-coding RNAs. More than 20,000 genes have been found in humans that code for piRNAs while only 2000 genes have been found for miRNAs. piRNAs can act at the transcriptional and post-transcriptional levels and have a vital role in silencing transposable elements present in germ cells. They are also involved in epigenetic silencing and activation. Previously, they were thought to function only in germ cells but new evidence suggests...
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