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Updated: Oct 16, 2025

Evaluation of Caspase Activation to Assess Innate Immune Cell Death
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eccDNAは,高固有の免疫刺激活性を持つアポプトティックな産物である

Yuangao Wang1,2, Meng Wang1,2, Mohamed Nadhir Djekidel1,2

  • 1Howard Hughes Medical Institute, Boston, MA, USA.

Nature
|October 21, 2021
PubMed
まとめ

エクストラクロモソームの円形DNA要素 (eccDNAs) は,アポトーシス中のランダムなDNA断片結合によって生成される. これらの円形のDNA分子は 強力な先天的な免疫刺激剤として働き スティング経路を活性化します

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