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Updated: Oct 15, 2025

Author Spotlight: Investigating the Motion Dynamics of the Eukaryotic Replisome Components at the Single-Molecule Level
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Author Spotlight: Investigating the Motion Dynamics of the Eukaryotic Replisome Components at the Single-Molecule Level

Published on: July 26, 2024

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ユカリオットの複製体分解を制御する保存されたメカニズム

Michael Jenkyn-Bedford1, Morgan L Jones1, Yasemin Baris1

  • 1MRC Laboratory of Molecular Biology, Cambridge, UK.

Nature
|October 26, 2021
PubMed
まとめ

DNA複製の最終段階である複製体分解は,CMGヘリケーゼのユビキティレーションによって制御される. 複製フォークのDNAは,早すぎるCMGの普遍化を防止し,ゲノムの安定性を確保します.

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