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Updated: Oct 14, 2025

Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo
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Chemical Conjugation of a Purified DEC-205-Directed Antibody with Full-Length Protein for Targeting Mouse Dendritic Cells In Vitro and In Vivo

Published on: February 5, 2021

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遠隔二次結合ポケットはDC-SIGNのヘテロマルチバレンタルターゲティングを促進します

Robert Wawrzinek1, Eike-Christian Wamhoff1,2, Jonathan Lefebre1,2

  • 1Department of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, 14424 Potsdam, Germany.

Journal of the American Chemical Society
|November 8, 2021
PubMed
まとめ

研究者らは,特別に設計されたリポソームを使用して,特定の樹状細胞 (DCs) をターゲットにする新しい方法を発見しました. この方法は,DCSの重要な受容体であるDC-SIGNの二次結合ポケットを利用して免疫反応を強化します.

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