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Updated: Oct 13, 2025

Assessment of Open Probability of the Mitochondrial Permeability Transition Pore in the Setting of Coenzyme Q Excess
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ミトキノンは,クライアント結合部位を遮断することによって,ミトコンドリアチャペロンTRAP1を無効化する

Nam Gu Yoon1, Hakbong Lee1, So-Yeon Kim1

  • 1Department of Biological Sciences, Ulsan National Institutes of Science and Technology (UNIST), Ulsan 44919, South Korea.

Journal of the American Chemical Society
|November 11, 2021
PubMed
まとめ

ミトキノン (MitoQ) は,そのクライアント部位に結合することによってミトコンドリアのHsp90 (TRAP1) を抑制し,強力な抗癌薬の開発のための新しい戦略を提供します. このアプローチは 効果的ながん治療の 可能性を示しています

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