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Updated: Oct 13, 2025

Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells
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Selection-dependent and Independent Generation of CRISPR/Cas9-mediated Gene Knockouts in Mammalian Cells

Published on: June 16, 2017

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タイプVのCRISPRトランポゾンシステムによる標的部位の選択と再構成

Irma Querques1, Michael Schmitz1, Seraina Oberli1

  • 1Department of Biochemistry, University of Zurich, Zurich, Switzerland.

Nature
|November 11, 2021
PubMed
まとめ

研究者はCRISPR関連トランポゾンによるRNA誘導DNAトランポシションのメカニズムを明らかにした. 構造と生化学の研究は Cas12k が DNA 挿入をどのように誘導し,新しい遺伝子編集ツールを可能にすることを示しています.

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