心臓門の解体と祖先のチューニケート・セシリティ
Alfonso Ferrández-Roldán1,2, Marc Fabregà-Torrus1,2, Gaspar Sánchez-Serna1,2
1Departament de Genètica, Microbiologia i Estadística, Facultat de Biologia, Universitat de Barcelona, Barcelona, Spain.
Nature
|November 18, 2021
まとめ
虫垂体細胞は 祖先の遺伝子を失い 心臓臓の遺伝子制御ネットワークを 解体して進化しました これは,シシールからフリーライフスタイルへの進化のシフトを支えている.
科学分野:
- 進化生物学
- 発達生物学
- 遺伝学
背景:
- 状のライフスタイルの進化,特にアシディアのセシリティとフリーライフのアペディキュラリアンスタイルの進化は重要な問題です.
- 心臓臓の遺伝子規制ネットワークは,状体のライフスタイル進化を理解するために不可欠であると仮定されています.
- 遺伝子制御ネットワークの進化を理解することで 異なる生命戦略の間の移行の洞察が得られます
研究 の 目的:
- カーディオファリンゲスの遺伝子調節ネットワークが ツニカトのライフスタイルにおける 進化的分岐に及ぼす役割を調査する.
- アプデキュラリアン・フリーライフスタイルが 原始的か 誘導的か 判断する
- 静止型からペラジック型への移行の遺伝的根拠を明らかにする.
主な方法:
- カーディオファリンジアル遺伝子の比較ゲノム解析
- 心房の遺伝子制御ネットワーク内の遺伝子損失とサブ機能の変化を調査する.
- 祖先のトニケート遺伝子制御ネットワークと ライフスタイルの進化を再構築する
主要な成果:
- 尾症の患者には 心臓の遺伝子や副機能が 大きく損なわれています
- この遺伝子の喪失は,先祖のツニケート心臓管遺伝子の規制ネットワークモジュールの解体につながった.
- デコンストラクションはシフォンの筋肉の発達が失われ,祖先のツニカットは座っていることを示唆している.
- 遺伝子の分解により 心臓の形成が加速し 臓の心臓を 体型に変えました
結論:
- 付属体の進化には 遺伝子の損失と 祖先の遺伝子の制御ネットワークの"解体"が 含まれていた.
- この遺伝的改造は 安定したアシディアンのような祖先から 自由に生きるアペンディキュラリアン形への 進化の軌道を支えています
- この発見は 衣類類の適応放射線と その多様な生活様式について 遺伝的説明を提供している.
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