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Updated: Oct 13, 2025

A Pipeline to Investigate the Structures and Signaling Pathways of Sphingosine 1-Phosphate Receptors
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Published on: June 8, 2022

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RGS7-Gβ5信号複合体と結合したヒトGPR158受容体の冷凍-EM構造

Dipak N Patil1, Shikha Singh2, Thibaut Laboute1

  • 1Department of Neuroscience, The Scripps Research Institute, Jupiter, FL 33458, USA.

Science (New York, N.Y.)
|November 18, 2021
PubMed
まとめ

研究者らは,Gタンパク質結合受容体158 (GPR158) の構造を発見し,そのホモディマー組織と異常なキャッシュドメインを明らかにした. これは孤児受容体の機能とシグナリング複合体の形成に関する重要な洞察を提供します.

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