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Updated: Oct 13, 2025

In vivo Application of the REMOTE-control System for the Manipulation of Endogenous Gene Expression
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ゲノム監視は,HUSH媒介によるイントロンレス移動要素の静音化

Marta Seczynska1, Stuart Bloor1, Sergio Martinez Cuesta2

  • 1Cambridge Institute for Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK.

Nature
|November 18, 2021
PubMed
まとめ

ヒューマン・サイレッシング・ハブ (HUSH) コンプレックスは 侵入したDNAを 特定し,静止させ,レトロウイルスのように イントロンのない遺伝子要素をターゲットにします. このメカニズムは ゲノムを外来DNAから保護します

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