関連する実験動画

Updated: Oct 12, 2025

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix
10:21

Scanning Electron Microscopy of Macerated Tissue to Visualize the Extracellular Matrix

Published on: June 14, 2016

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心不全における細胞外マトリックス: プロテオグリカン再構成におけるADAMTS5の役割

Javier Barallobre-Barreiro1, Tamás Radovits2, Marika Fava1

  • 1King's BHF Centre of Research Excellence, London, UK (J.B.-B., M.F., U.M., W.-Y.L., E.E., E.D., M.H., L.E.S., B.S., R.L., F.B., A.M.S., N.C., K.T., A.M.S., M.M.).

Circulation
|November 22, 2021
PubMed
まとめ

ADAMTSプロテアゼは,心の中でヴァルシカンを分解し,その蓄積は心不全 (HF) で心機能を損なう. ベータブロッカーは,ヴァルシカンの蓄積を減らし,HF患者の心臓細胞外マトリクスを改善する可能性があります.

キーワード:
アドレナージックβアゴニスト細胞外マトリックス心不全プロテオグリカン

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Isolation of Atrial Cardiomyocytes from a Rat Model of Metabolic Syndrome-related Heart Failure with Preserved Ejection Fraction08:31

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